Detalhe da pesquisa
1.
A multi-scale map of cell structure fusing protein images and interactions.
Nature
; 600(7889): 536-542, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34819669
2.
Active Interaction Mapping Reveals the Hierarchical Organization of Autophagy.
Mol Cell
; 65(4): 761-774.e5, 2017 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28132844
3.
A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy.
Mol Cell
; 63(3): 514-25, 2016 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27453043
4.
Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA.
Mol Cell
; 62(2): 157-168, 2016 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27105112
5.
Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.
Nat Methods
; 14(6): 573-576, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28319113
6.
De novo generation of multi-target compounds using deep generative chemistry.
Nat Commun
; 15(1): 3636, 2024 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38710699
7.
Coevolution within a transcriptional network by compensatory trans and cis mutations.
Genome Res
; 20(12): 1672-8, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20978140
8.
Interpretation of cancer mutations using a multiscale map of protein systems.
Science
; 374(6563): eabf3067, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34591613
9.
Genome-Wide Dynamic Evaluation of the UV-Induced DNA Damage Response.
G3 (Bethesda)
; 10(9): 2981-2988, 2020 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32732306
10.
Quantitative Translation of Dog-to-Human Aging by Conserved Remodeling of the DNA Methylome.
Cell Syst
; 11(2): 176-185.e6, 2020 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32619550
11.
Ultrahigh-Density Screens for Genome-Wide Yeast EMAPs in a Single Plate.
Methods Mol Biol
; 2049: 73-85, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31602605
12.
Disruption of NSD1 in Head and Neck Cancer Promotes Favorable Chemotherapeutic Responses Linked to Hypomethylation.
Mol Cancer Ther
; 17(7): 1585-1594, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29636367
13.
A global transcriptional network connecting noncoding mutations to changes in tumor gene expression.
Nat Genet
; 50(4): 613-620, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29610481
14.
Translation of Genotype to Phenotype by a Hierarchy of Cell Subsystems.
Cell Syst
; 2(2): 77-88, 2016 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26949740
15.
Chemogenetic profiling identifies RAD17 as synthetically lethal with checkpoint kinase inhibition.
Oncotarget
; 6(34): 35755-69, 2015 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26437225
16.
Decoupling epigenetic and genetic effects through systematic analysis of gene position.
Cell Rep
; 3(1): 128-37, 2013 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-23291096
17.
A UV-induced genetic network links the RSC complex to nucleotide excision repair and shows dose-dependent rewiring.
Cell Rep
; 5(6): 1714-24, 2013 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-24360959
18.
Rewiring of genetic networks in response to DNA damage.
Science
; 330(6009): 1385-9, 2010 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-21127252